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WISER for Windows
Download - Version 5.3.14 (Feb 21,2019 03:49:40 PM)

Use the button below to download the installer for WISER.

The WISER application requires at least 28 megabytes of hard disk space and the Microsoft® .NET Framework 4.6.1 SP1. The WISER installer will automatically detect if an installation/upgrade of .NET is required on your computer, and if Internet connectivity is available it will automatically download and install it. .NET can also be downloaded/installed separately from here.

Windows 7 installations require service pack 1. The required .NET 4.6 installation may take time to download and install. Please be patient during your installation.

View the README for system requirements, installation instructions, and release notes.

Previous versions of WISER (5.0 or below) should be uninstalled. The 5.1 release features a new installer, which will overwrite future versions of WISER automatically.

Some users may see a warning from Windows Defender SmartScreen noting that the download is an unrecognized app even though the download file is signed with a current certificate from the National Library of Medicine. If this occurs, do the following:

  1. Select "More Info"
  2. Press the "Run anyway" button.
  3. Proceed with the installation.

System Administrator Install

This install is targeted at system administrators that would like to install WISER for Windows to multiple computers. It is identical to the download above but doesn't include the required .NET Framework, which must be downloaded and installed separately. System administrators should do the following:

  1. Install the .NET Framework version 4.6.1. System Administrators can find more information regarding .NET Framework deployments here.
  2. Install the following download, a WISER for Windows MSI Installer.

WISER Documentation

The WISER User Guide is included in the above downloads, and is also available separately here. Requires Adobe® Reader®, freely available at

View the WISER Substance List